Author

Austin J. Stoner

Yale UniversityORCID 0000-0002-3788-9347Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:mouse· 1 Assay:snRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Chao ZhengiD· 1 shared Joshua M. SpurrieriD· 1 shared LaShae NicholsoniD· 1 shared Li FuiD· 1 shared Stephen M. StrittmatteriD· 1 shared Takuya ToyonagaiD· 1 shared Will LairdiD· 1 shared Zhengxin CaiiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperNeuroscience

Chao ZhengORCID

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1 paper

Recent·Most cited

Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss in Alzheimer's Knock-in Mice Require Cellular Prion Protein

Austin J. Stoner, Li Fu, LaShae Nicholson, Chao Zheng, Takuya Toyonaga, Joshua M. Spurrier, Will Laird, Zhengxin Cai, Stephen M. Strittmatter

This study shows that PrPC is necessary for synapse loss, phospho-tau accumulation, and neuronal gene expression changes in Alzheimer's knock-in mice, suggesting targeting the Aβo-PrPC interaction could prevent these pathologies.

bioRxiv · Feb 15, 2023 · PreprintNeuroscience