Lingshuang Wu

Optimizing Oxylipin Analysis with Liquid Chromatography Mass Spectrometry through Bio-Inert Systems and Ion Funnel Adjustments

This study optimizes LC-MS methods for oxylipin quantification in human plasma by using bio-inert systems and adjusting ion funnel voltages, improving signal and compound detection.

Nir1-Nir2 Heterodimerization Expands the Sensitivity and Dynamic Range of the Phosphatidylinositol Cycle

This study identifies a conserved NirD domain that mediates Nir1-Nir2 heterodimerization, enhancing PIP2 replenishment and expanding the dynamic range of the phosphatidylinositol cycle.

Dithionite quenching of NBD-labeled lipids reveals artificial lipid droplet purity and neutral lipid surface accessibility

DDHD2 possesses both lipase and transacylase capacities that remodel triglyceride acyl chains

This paper identifies DDHD2 as a neutral lipid lipase and transacylase that remodels triglyceride acyl chains by transferring acyl groups between lipids.

Biallelic variants in POPDC2 cause a novel autosomal recessive syndrome presenting with cardiac conduction defects and variable hypertrophic cardiomyopathy