Jen Liou

This study identifies a conserved NirD domain that mediates Nir1-Nir2 heterodimerization, enhancing PIP2 replenishment and expanding the dynamic range of the phosphatidylinositol cycle.

This study shows that the CCC complex regulates PI(3)P levels on phagosomal membranes, which is critical for phagosome maturation and antibacterial immunity.

This study shows PM curvature promotes ER-PM contact formation in cardiomyocytes via junctophilin-EHD interactions.

This study shows EB1 binding acts as a diffusion trap to regulate STIM1 localization and Ca2+ signaling by delaying its translocation to ER-PM junctions.