Samuel E. Lacey

The paper visualizes axoneme assembly in situ using cryo-electron tomography and identifies conserved microtubule luminal proteins and assembly intermediates.

This study uses cryo-electron tomography and AlphaFold2 to model the structure of anterograde intraflagellar transport trains and elucidate their polymerization mechanism.

The paper uses cryo-EM to determine the structure of dynactin's shoulder and pointed end, revealing their architecture and subunit interactions.

The paper uses cryo-EM to determine the structure of dynein microtubule-binding domains, revealing structural differences between cytoplasmic and axonemal dyneins that may affect microtubule distortion.