Author
MRC Laboratory of Molecular BiologyORCID 0000-0003-1083-2989Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Akancha Mishra, Giedrė Ratkevičiūtė, Amy Ibrahim…·Clinton K. Lau
The paper identifies GAPM2 as an IMC component in Plasmodium species and reveals its heterotrimeric complex structure and functional role in the glideosome.
Kashish Singh, Clinton K. Lau, Giulia Manigrasso…·Andrew P. Carter
This study determines the cryo-EM structure of dynein-dynactin with LIS1 and JIP3, revealing how these regulators enable complex formation and function.
Clinton K. Lau, Francis J. O’Reilly, Balaji Santhanam…·Andrew P. Carter
The paper uses cryo-EM to determine the structure of dynactin's shoulder and pointed end, revealing their architecture and subunit interactions.
Girish R. Mali, Ferdos Abid Ali, Clinton K. Lau…·Andrew P. Carter
The paper identifies two factors, Q22YU3 and Q22MS1, that package axonemal outer dynein arms for ciliary targeting in Tetrahymena.
Linas Urnavicius, Clinton K. Lau, Mohamed M. Elshenawy…·Andrew P. Carter
The paper shows that adaptors like BICDR1 and HOOK3 recruit two dyneins to dynactin, increasing force and speed compared to BICD2's single dynein recruitment.