Sachin Kumar

Inflammasomes and DNA Damage Orchestrate Divergent Pyroptotic Fates in Neutrophils

This study investigates pyroptotic responses in neutrophils under different conditions, revealing distinct mechanisms involving inflammasomes, DNA damage, and actomyosin forces that determine cytokine secretion or cell death.

Sca-1 expression depicts pro-inflammatory murine neutrophils under steady state and pathological conditions

This study identifies a novel Sca1pos neutrophil subset with pro-inflammatory properties in both steady state and inflammatory conditions.

Elucidating key determinants of engineered scFv antibody in MMP-9 binding using high throughput screening and machine learning

The paper uses high-throughput screening and machine learning to identify key determinants of scFv antibody binding to MMP-9.

Post-transcriptional regulation of adult CNS axonal regeneration by Cpeb1

This study identifies post-transcriptional regulation by Cpeb1 as a mechanism enhancing CNS axonal regeneration in mice and Drosophila.