Author

Manuel Göpferich

German Cancer Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

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Organism:mouse· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

Ana Martín-VillalbaiD· 4 shared Damian Carvajal IbañeziD· 2 shared Georgios KalamakisiD· 2 shared Maxim A. Skabkin· 2 shared Raúl MéndeziD· 2 shared Simon AndersiD· 2 shared Adrien JollyiD· 1 shared Alejandro Santos Lopez· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersNeuroscience

Ana Martín-VillalbaORCID

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4 papers

Recent·Most cited

Interferon regulates stem cell function at all ages by orchestrating mTOR and cell cycle

Damian Carvajal Ibañez, Maxim A. Skabkin, Jooa Hooli, Santiago Cerrizuela, Manuel Göpferich, Adrien Jolly, Marc Zumwinkel, Matilde Bertolini, Thomas Höfer, Guenter Kramer, Simon Anders, Aurelio Telemann, Anna K. Marciniak-Czochra, Ana Martín-Villalba

This study shows interferon regulates stem cell function across all ages by controlling mTOR and cell cycle, with beneficial effects in youth and harmful effects in aging brains.

bioRxiv · Feb 3, 2022 · PreprintNeuroscience

Single cell 3'UTR analysis identifies changes in alternative polyadenylation throughout neuronal differentiation and in autism

Manuel Göpferich, Nikhil Oommen George, Ana Domingo-Muelas, Alex Bizyn, Rosa Pascual, Daria Fijałkowska, Georgios Kalamakis, Ulrike Müller, Jeroen Krijgsveld, Raúl Méndez, Isabel Fariñas, Wolfgang K. Huber, Simon Anders, Ana Martín-Villalba

The paper analyzes 3'UTR changes during neuronal differentiation and in ASD, finding longer 3UTRs in ASD patients and a role for CPEB4 and APLP1 in APA regulation.

bioRxiv · Aug 12, 2020 · PreprintNeuroscience

Onset of differentiation is posttranscriptionally controlled in adult neural stem cells

Avni Baser, Maxim A. Skabkin, Susanne Kleber, Yonglong Dang, Gülce S. Gülcüler Balta, Georgios Kalamakis, Manuel Göpferich, Damian Carvajal Ibañez, Roman Schefzik, Alejandro Santos Lopez, Enric Llorens-Bobadilla, Carsten Schultz, Bernd Fischer, Ana Martín-Villalba

The paper shows that posttranscriptional regulation, specifically translational repression, controls the onset of differentiation in adult neural stem cells.

Nature · Jan 30, 2019Peer-reviewedNeuroscience

Post-transcriptional regulation of adult CNS axonal regeneration by Cpeb1

Wilson Pak-Kin Lou, Álvaro Mateos, Marta Koch, Stefan Klußmann, Chao Yang, Na Lü, Sachin Kumar, Stefanie Limpert, Manuel Göpferich, Marlen Zschaetzsch, Christopher Sliwinski, Marc Kenzelmann, Matthias Seedorf, Carlos Maillo, Elena Senís, , Ana Martín-Villalba

This study identifies post-transcriptional regulation by Cpeb1 as a mechanism enhancing CNS axonal regeneration in mice and Drosophila.

Frontiers in Molecular Neuroscience · Jan 12, 2018Peer-reviewedNeuroscience