Pratul K. Agarwal

This study shows that APE1's Asn174 residue stabilizes the AP-site through hydrogen bonding and electrostatic interactions, which are essential for catalytic activity.

This study identifies a novel non-catalytic function of PcrP, a PA2803 subfamily protein, which contributes to polymyxin B resistance in P. aeruginosa through protein interactions and Ca2+-dependent mechanisms.

This study uses computational methods to analyze dynamic differences among Pen β-lactamases from Burkholderia spp., identifying critical mutations and functional hotspots.

The paper analyzes SARS-CoV-2 mutations across 8 million sequences to identify high-mutability proteins and predict surges, providing real-time genomic surveillance.

The paper predicts future COVID-19 surges by analyzing SARS-CoV-2 mutations in real time using genomic surveillance data.