Author
Howard Hughes Medical InstituteORCID 0000-0003-1538-6367Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Kaitlin M. DeHart, Nicole M. Hoitsma, Spencer H. Thompson…·Bret Freudenthal
This study shows that APE1's Asn174 residue stabilizes the AP-site through hydrogen bonding and electrostatic interactions, which are essential for catalytic activity.
Chelsea Marie Toner, Nicole M. Hoitsma, Sashi R. Weerawarana, Karolin Luger
The paper reports the structure of nucleosomes formed by Medusavirus medusae histones, showing similarities to eukaryotic and Melbournevirus nucleosomes and revealing unique features of viral histone function.
Sidrit Uruci, Nicole M. Hoitsma, María Eugenia Soler-Oliva…·Nitika Taneja
This study shows SMARCAD1 resolves R-loops at replication forks, preventing genome instability and cancer mutations.