Author

Hasan Uğurlu

University of HelsinkiORCID 0000-0002-3849-7847Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Organism:virus· 1

Frequent Co-Authors

Anna R. MäkeläiD· 2 shared Ilona RissaneniD· 2 shared Kalle SakselaiD· 2 shared Petja SalmineniD· 2 shared Andres MeritsiD· 1 shared Ashwini KedariiD· 1 shared Eva ŽusinaiteiD· 1 shared Lev LevanoviD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Anna R. MäkeläORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 3, 2024

Spike conformational tuning rather than epitope erosion drives SARS-CoV-2 resistance to broadly neutralizing antibodies

Riku Fagerlund, Hasan Uğurlu, Petja Salminen…·Kalle Saksela

The paper shows that SARS-CoV-2 resistance to broadly neutralizing antibodies is due to altered spike conformational dynamics, not epitope mutations.

1 citation

virusexperimental assay

𝕏 PostBluesky

Molecular BiologyStructurePeer-reviewedOct 28, 2024

Structural insight into rabies virus neutralization revealed by an engineered antibody scaffold

Ashwini Kedari, Rommel Paneth Iheozor-Ejiofor, Petja Salminen…·Ilona Rissanen

This paper determines the crystal structure of an engineered antibody diabody bound to rabies virus glycoprotein, revealing a conserved epitope and mechanism of neutralization.

7 citations

protein structureexperimental assay

𝕏 PostBluesky