Author

Hai‐Bin Ruan

University of MinnesotaORCID 0000-0002-3858-1272Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alessandro BartolomucciiD· 2 shared Chenxin Gu· 2 shared Endre KristófiD· 2 shared Eric D. QueathemiD· 2 shared Patrycja PuchalskaiD· 2 shared Peter A. CrawfordiD· 2 shared Rini AriantiiD· 2 shared Xuechun ChangiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

Alessandro BartolomucciORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologyJournal of NeuroinflammationPeer-reviewedOct 1, 2026

Complement 3a Receptor mediates high fat diet induced hypothalamic accumulation of lipid associated microglia to regulate neuroinflammation and obesity

Jean Pierre Pallais, Maria Razzoli, Pedro Rodriguez…·Alessandro Bartolomucci

This study identifies C3aR as a mediator of HFD-induced hypothalamic microgliosis and obesity, showing its role in lipid droplet formation and neuroinflammation.

DOI 10.1186/s12974-026-04063-z

mousebulk RNA-seq

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PhysiologybioRxivPreprintJun 13, 2025

Ketone body driven lipid remodeling supports thermogenic adaptation to fasting

Zahra Moazzami, Eric D. Queathem, Jiawen Ma…·Hai‐Bin Ruan

The paper shows that ketone bodies support thermogenic adaptation in BAT during fasting by promoting lipid remodeling and thermogenesis.

1 citation

mousemetabolomics

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BiochemistryScience AdvancesPeer-reviewedJan 29, 2025

Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation

Eric D. Queathem, Zahra Moazzami, David B. Stagg…·Patrycja Puchalska

The paper shows ketogenesis supports PUFA homeostasis in hepatocytes by enabling FA elongation, and its disruption leads to lipid imbalances similar to MASLD.

32 citationstop 1%

mousemetabolomics

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Developmental BiologybioRxivPreprintJun 16, 2023

Supraclavicular brown adipocytes originate from Tbx1+ myoprogenitors

Zan Huang, Chenxin Gu, Zengdi Zhang…·Hai‐Bin Ruan

This study identifies Tbx1+ myoprogenitors as the developmental origin of supraclavicular brown adipocytes in mice and shows their relevance in human deep neck BAT.

1 citation

mousehuman

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