Author

Ryan J. Gleason

Johns Hopkins UniversityORCID 0000-0002-3859-1390Unclaimed ORCID profile · follow to get notified of new preprints

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Ryan J. Gleason1 paper

Biology Disciplines

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Developmental Biology· 2 Genomics· 1

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Research Focus:gene regulatory network inference· 3 Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Approach:statistical model· 2

Frequent Co-Authors

Xin CheniD· 3 shared Binbin MaiD· 1 shared Brendon E. M. DavisiD· 1 shared Christopher S. SemancikiD· 1 shared Daniel RingwaltiD· 1 shared Gitanjali LakshminarayananiD· 1 shared Guanghui YangiD· 1 shared Jennifer A. UrbaniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersDevelopmental Biology

Xin ChenORCID

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3 papers

Recent·Most cited

GenomicsGenome ResearchPeer-reviewedDec 10, 2025

Cell type- and chromosome-specific chromatin landscapes and DNA replication programs of Drosophila testis tumor stem-cell like cells

Jennifer A. Urban, Daniel Ringwalt, John M. Urban…·Xin Chen

DOI 10.1101/gr.280809.125

DrosophilascRNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintSep 19, 2024

Modulating DNA Polα Enhances Cell Reprogramming Across Species

Rajesh Ranjan, Binbin Ma, Ryan J. Gleason…·Xin Chen

This study shows that reducing DNA Polα levels enhances cell reprogramming across species, improving fertility and tissue regeneration without affecting lifespan.

1 citation

DrosophilaC. elegans

𝕏 PostBluesky

Developmental BiologybioRxivPreprintMar 1, 2022

Developmentally programmed epigenome regulates cellular plasticity at the parental-to-zygote transition

Ryan J. Gleason, Christopher S. Semancik, Gitanjali Lakshminarayanan, Xin Chen

The paper shows that an epigenome switch from H3 to H3.3 to H3 during C. elegans development is essential for germline integrity and early embryonic plasticity.

DOI 10.1101/2022.03.01.482564

C. elegansChIP-seq

𝕏 PostBluesky