Author

Rolando A. Cuevas

University of PittsburghORCID 0000-0002-3571-5845Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Cynthia St. HilaireiD· 3 shared Parya BehzadiiD· 2 shared Adeyeye I. HaastrupiD· 1 shared Alex CraneiD· 1 shared Allison L. KuipersiD· 1 shared André Ferreira do NascimentoiD· 1 shared Andrew A. Wendling· 1 shared Angela Russ· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersPhysiology

Cynthia St. HilaireORCID

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3 papers

Recent·Most cited

Therapeutic potential of Relaxin-2 in Heart Failure with preserved Ejection Fraction (HFpEF)

Joshua B. Palma, Beth A. Gabris-Weber, Brenda McMahon, Anthony J. Mauro, Cynthia St. Hilaire, Rolando A. Cuevas, Thomas Bernd Dschietzig, Guillermo Romero, Guy Salama

This study investigates the therapeutic effects of synthetic Relaxin-2 in HFpEF, showing it reverses diastolic dysfunction and reduces arrhythmia vulnerability in ZSF1 rats.

bioRxiv · May 18, 2026 · PreprintPhysiology

Progranulin deficiency aggravates aging-induced vascular injury

Renata de Azevedo Melo Luvizotto, André Ferreira do Nascimento, Gustavo Félix Pimenta, Rafael Menezes da Costa, Shubhnita Singh, Juliano V Alves, Wanessa M.C. Awata, Angela Russ, Adeyeye I. Haastrup, Rolando A. Cuevas, Parya Behzadi, Cynthia St. Hilaire, Justin T. Roberts, Ariane Bruder‐Nascimento, Thiago B Bruder-Nascimento

This study shows that progranulin deficiency worsens age-related vascular damage in mice, affecting endothelial function and vascular remodeling.

bioRxiv · Nov 25, 2025 · PreprintCell Biology

Rapamycin Reduces Arterial Mineral Density and Promotes Beneficial Vascular Remodeling in a Murine Model of Severe Medial Arterial Calcification

Parya Behzadi, Andrew A. Wendling, Rolando A. Cuevas, Alex Crane, Claire C. Chu, William J. Moorhead, Ryan Wong, Mark J. Brown, Joshua Tamakloe, Swathi Suresh, Payam Salehi, Iris Zamir Jaffe, Allison L. Kuipers, Lyudmila Lukashova, Konstantinos Verdelis, Cynthia St. Hilaire

This study shows rapamycin reduces arterial mineral density and improves vascular structure in Mgp-/- mice with medial arterial calcification, though calcification volume remains unchanged.

American Journal of Physiology-Heart and Circulatory Physiology · May 8, 2025Peer-reviewedPhysiology