Author

Ben J. Greenwell

Texas A&M UniversityORCID 0000-0002-3879-7946Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Jérôme S. MenetiD· 3 shared Alexandra J. TrottiD· 2 shared Joshua R Beytebiere· 2 shared Carolina EscobariD· 1 shared Christine MerliniD· 1 shared Collin A. Osborne· 1 shared Deborah Bell‐PederseniD· 1 shared Hélène VitetiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersGenomics

Jérôme S. MenetORCID

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3 papers

Recent·Most cited

Lack of food intake during shift work alters the heart transcriptome and leads to cardiac fibrosis and inflammation in rats

Alexandra J. Trott, Ben J. Greenwell, Tejas R. Karhadkar, Natalí N. Guerrero‐Vargas, Carolina Escobar, Ruud M. Buijs, Jérôme S. Menet

This study shows that shift work in rats alters heart gene expression, leading to fibrosis and inflammation when food is restricted during work hours, but not when food is available.

bioRxiv · May 13, 2021 · PreprintGenomics

Isoform-specific regulation of rhythmic gene expression by alternative polyadenylation

Ben J. Greenwell, Joshua R Beytebiere, Teresa M. Lamb, Deborah Bell‐Pedersen, Christine Merlin, Jérôme S. Menet

The paper shows that rhythmic gene expression in mouse liver is largely regulated by isoform-specific alternative polyadenylation, with rhythmic APA isoforms generating 24-hour rhythms in 3' UTR length.

bioRxiv · Dec 12, 2020 · PreprintMolecular Biology

Tissue-specific BMAL1 cistromes reveal that enhancer-enhancer interactions regulate rhythmic transcription

Joshua R Beytebiere, Alexandra J. Trott, Ben J. Greenwell, Collin A. Osborne, Hélène Vitet, Jessica Spence, Seung Hee Yoo, Zheng Chen, Joseph S. Takahashi, Noushin Ghaffari, Jérôme S. Menet

The paper shows BMAL1 DNA binding is tissue-specific and regulates rhythmic transcription through enhancer-enhancer interactions in the mouse liver.

Genes & Development · Mar 1, 2019Peer-reviewedGenetics