Brian P. Lazzaro

This study examines how host plant nutrition and microbial interactions affect fitness in Drosophila mettleri using laboratory media formulations.

This study develops a mathematical model showing that bacterial corpses can influence infection dynamics and immune evolution by both hindering pathogen control and protecting against autoimmune damage.

This study shows that strong GAL4 expression in Drosophila fat body causes physiological defects, including reduced lipid stores and infection resistance, and identifies factors that influence these effects.

This paper introduces a method to isolate Drosophila fat body nuclei for transcriptomic analysis, showing improved transcript capture and reduced mitochondrial contamination.

This study investigates the genetic basis of Drosophila melanogaster's defense against Beauveria bassiana using QTL mapping and evolve and resequence approaches, revealing genetic variation and trade-offs in immune defense.

The paper develops a bioinformatics pipeline to integrate Drosophila melanogaster genomic data from diverse sources, creating a large dataset called DEST for population genetics analysis.

The paper uses computational models to show that host-pathogen feedbacks can lead to divergent infection outcomes, even with similar initial conditions.