Michael R. Drew

This study identifies paraventricular thalamus hyperactivity as a mechanism for stress-induced sensitization of unlearned fear, distinct from stress-enhanced fear learning.

The paper investigates how stress affects fear memory engrams in the dorsal and ventral dentate gyrus using the SEFL model and FosTRAP2 mice, finding stress enhances reactivation in the caudal DG but not the rostral DG.

This study shows extinction training suppresses fear memory ensembles across hippocampal regions and alters their transcriptomes, while creating a distinct extinction ensemble.

This study shows that NR2B-containing NMDA receptors on adult-born hippocampal neurons are necessary for (R,S)-ketamine's rapid-acting antidepressant effects in male and female mice.

This study shows that post-stroke SVZ-derived cells provide trophic support for neural repair rather than replacing damaged cells, with VEGF playing a key role in recovery.

This study shows that acute social stress enhances learning of appetitive cues via synergistic CRF and NE signaling in the VTA, promoting Pavlovian reward conditioning.