Author

Ramakumar Tummala

University of ToledoORCID 0000-0002-3887-3566Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Beng San YeohiD· 2 shared Bina JoeiD· 2 shared Blair MelliD· 2 shared Ishan ManandhariD· 2 shared Matam Vijay–KumariD· 2 shared Piu SahaiD· 2 shared Sachin AryaliD· 2 shared Xue MeiiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersPhysiology

Beng San YeohORCID

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2 papers

Recent·Most cited

The Herbicide Glyphosate Promotes Hypertension via Gut Microbiota-Mediated Mechanisms

Ishan Manandhar, Sudhan Pachhain, Ramakumar Tummala, Blair Mell, Arturo Grano de Oro, Sachin Aryal, Xue Mei, Maya Nair, Sanjana Kumariya, Wisdom Ahildja, Oluwatosin Mautin Akinola, Pritam Bardhan, Tao Yang, Beng San Yeoh, Yuan Tian, , Bina Joe

This study shows glyphosate exposure increases blood pressure through gut microbiota-mediated disruption of FXR-signaling and shikimic acid accumulation.

bioRxiv · Feb 27, 2026 · PreprintPhysiology

Ketone body mediated histone β-hydroxybutyrylation is reno-protective

Juthika Mandal, Sachin Aryal, Ishan Manandhar, Saroj Chakraborty, Xue Mei, Beng San Yeoh, Blair Mell, Andrew L. Kleinhenz, Ramakumar Tummala, Tao Yang, Piu Saha, William T. Gunning, Matam Vijay–Kumar, Venkatesha Basrur, Ivana L. de la Serna, Bina Joe

This study shows that ketone body-mediated histone β-hydroxybutyrylation in the kidney regulates chromatin structure to promote energy metabolism and suppress immune responses, offering renoprotection.

Hypertension · Jul 29, 2025Peer-reviewedPhysiology