Synthetic BiologybioRxivPreprint
Conjugative serine recombinase engineering enables genome integration in transformation-resistant bacteria and bioproduction pathway prototyping
Michael S. Guzman, Cholpisit Kiattisewee, Amanda M. Robert…·James M. Carothers
This paper introduces cSAGE, a conjugation-based genome engineering platform that enables site-specific integration in transformation-resistant bacteria, demonstrating its utility in bioproduction pathway prototyping.
DOI 10.64898/2026.04.17.717921