Author

Hanke Gwendolyn Bauersachs

European Molecular Biology LaboratoryORCID 0000-0002-3918-7162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Annique ClaringbouldiD· 2 shared Judith B. ZauggiD· 2 shared Nila H. ServaasiD· 2 shared Christian ArnoldiD· 1 shared Evi P. VlachouiD· 1 shared Frank SteiniD· 1 shared Ivan BerestiD· 1 shared James P. ReddingtoniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Annique ClaringbouldORCID

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2 papers

Recent·Most cited

Integrative Multi-Omics Identifies CDK1 as a Key Signaling Regulator of CD4+ T Cell Effector Function

Nila H. Servaas, Hanke Gwendolyn Bauersachs, Luisa Abreu, Annique Claringbould, Ivan Berest, Jennifer Schwarz, Frank Stein, Maria Fälth-Savitski, Lena Eismann, James P. Reddington, Judith B. Zaugg

This study identifies CDK1 as a key regulator of CD4+ T cell effector function through integrative multi-omics analysis, showing its role in linking phosphorylation to gene regulation and immune traits.

bioRxiv · Oct 30, 2025 · PreprintGenomics

Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease

Sara Lobato-Moreno, Umut Yildiz, Annique Claringbould, Nila H. Servaas, Evi P. Vlachou, Christian Arnold, Hanke Gwendolyn Bauersachs, Víctor Campos-Fornés, Karin D. Prummel, Kyung‐Min Noh, Mikael Marttinen, Judith B. Zaugg

This paper introduces SUM-seq, a scalable multiomic method for single-cell chromatin and RNA sequencing, revealing gene regulatory dynamics in macrophage polarization linked to autoimmune diseases.

bioRxiv · Dec 26, 2023 · PreprintGenomics