Thomas Deller

This study shows that ATXN2 polyglutamine expansion impairs QKI-dependent alternative splicing and oligodendrocyte maintenance in a mouse model of SCA2.

The paper shows that the skewed spine size distribution in neurons is not affected by synaptic activity or plasticity and forms early in neuronal development.

This study investigates the role of amyloid precursor protein (APP) in synaptic transmission at medial perforant path synapses using organotypic cultures and finds that presynaptic APP affects neurotransmission efficacy.

This study shows that all-trans retinoic acid induces synaptopodin-dependent metaplasticity in mouse dentate granule cells without altering baseline synaptic transmission.

The paper shows that neuronal excitability in response to synaptic inputs is invariant to dendritic length, with voltage responses depending only on dendritic diameter and conductivity.

This study shows that amyloid-beta, not APP or its secreted fragments, mediates homeostatic synaptic plasticity in the absence of APP.

This study shows all-trans retinoic acid induces synaptic plasticity in human cortical neurons by causing structural and functional changes in excitatory synapses.

This study shows that Synaptopodin stabilizes dendritic spines over long-term by preventing their pruning, as demonstrated through time-lapse imaging in mouse organotypic cultures.

The paper investigates how systemic inflammation affects synaptic plasticity using repetitive magnetic stimulation and shows that anti-inflammatory cytokines can restore plasticity in inflamed tissue cultures.

The paper shows neuronal activity triggers uptake of hematopoietic extracellular vesicles in vivo, both under pathological and physiological conditions.