Ting Fu

This study shows that low-dose radiation increases cortical excitability in mice, suggesting potential therapeutic use for neuronal circuit disorders.

The paper identifies early brain state maladaptations in mouse and human neuroinflammation that contribute to disease progression independent of relapse activity.

The paper screens CNS-penetrant compounds to identify small molecules that modulate microglial phagocytosis of synaptosomes, finding 28 compounds with significant effects.

This study shows that knocking out CYFIP1 in human microglia reduces synaptic vesicle phagocytosis, morphology changes, and motility, suggesting a role in synaptic pruning related to neurodevelopmental disorders.

This study generates patient-derived microglia-like cells from umbilical cord blood to model fetal brain immune responses to maternal SARS-CoV-2 exposure.

The paper improves the specificity, reduces artifacts, and optimizes stimulation efficacy in two-photon all-optical neural circuit interrogation using mouse visual cortex.

The paper shows neuronal activity triggers uptake of hematopoietic extracellular vesicles in vivo, both under pathological and physiological conditions.

The paper shows increased microglial synapse elimination in schizophrenia patient models and links it to genetic variants and potential therapeutic interventions.