BioengineeringCell stem cellPeer-reviewed
Tunable differentiation of human CD4+ and CD8+ T cells from pluripotent stem cells
Ross D. Jones, Kevin Salim, Laura N Stankiewicz…·Peter W. Zandstra
This study shows how to generate CD4+ T cells from pluripotent stem cells by controlling Notch and T cell receptor signaling, enabling clonally diverse and expandable cells that can differentiate into helper cell types.
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