Author
University of British Columbia
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Ross D. Jones, Kevin Salim, Laura N Stankiewicz…·Peter W. Zandstra
This study shows how to generate CD4+ T cells from pluripotent stem cells by controlling Notch and T cell receptor signaling, enabling clonally diverse and expandable cells that can differentiate into helper cell types.
Christine M. Wardell, Vivian C. W. Fung, Eleanor Chen…·Megan K. Levings
A2-CAR Tregs reduce BDC2.5 T cell engraftment, proliferation, and cytokine production, protecting mice from diabetes and inducing systemic tolerance.
Dominic A. Boardman, Sonya Mangat, Jana K. Gillies…·Megan K. Levings
This study engineers CAR Tregs to secrete IL-10 via PDCD1-driven regulation, enhancing their suppressive function in vitro and in vivo.
Henry Y. Lu, Maryam Vaseghi‐Shanjani, Avery J. Lam…·Stuart E. Turvey
The paper describes a germline variant in IKZF2 causing immune dysregulation, including AIHA and atopic dermatitis, and reports single-cell RNA sequencing findings on T cell dysfunction.