Author

Scott W. Tighe

University of VermontORCID 0000-0002-3988-0741Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:benchmark study· 2 Research Focus:benchmarking· 2 Assay:metagenomics· 2 Organism:bacteria (other)· 1 Research Focus:ecology & biodiversity· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Christopher E. MasoniD· 2 shared Jonathan FooxiD· 2 shared Shawn LevyiD· 2 shared Alexa B. R. McIntyreiD· 1 shared Alicia AlonsoiD· 1 shared Brent PeytoniD· 1 shared Camilla UrbaniakiD· 1 shared Ceth W. ParkeriD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenomics

Christopher E. MasonORCID

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Author profile →

3 papers

Recent·Most cited

Differential efficiency of sampling devices in the measurement of microbial diversity of Yellowstone National Park hot springs

Jason M. Wood, Scott W. Tighe, Camilla Urbaniak, Ceth W. Parker, Nitin Kumar Singh, Season Wong, Brent Peyton, Kasthuri J. Venkateswaran

This study evaluates sampling devices for microbial diversity in Yellowstone hot springs, finding that filtration methods affect recovery of low-abundance taxa.

bioRxiv · Jun 18, 2026 · PreprintEcology

Multi-Platform Assessment of DNA Sequencing Performance using Human and Bacterial Reference Genomes in the ABRF Next-Generation Sequencing Study

Jonathan Foox, Scott W. Tighe, Charles M. Nicolet, Justin M. Zook, Marta S. Byrska‐Bishop, Wayne E. Clarke, Michael M. Khayat, Medhat Mahmoud, Phoebe K. Laaguiby, Zachary T. Herbert, Derek Warner, George S. Grills, Jin Jen, Shawn Levy, Jenny Xiang, , Christopher E. Mason

The paper assesses DNA sequencing performance across multiple platforms using human and bacterial reference genomes to evaluate quality and reproducibility.

bioRxiv · Jul 23, 2020 · PreprintGenomics

Comprehensive Benchmarking and Ensemble Approaches for Metagenomic Classifiers

Alexa B. R. McIntyre, Rachid Ounit, Ebrahim Afshinnekoo, Robert J. Prill, Elizabeth Marie Hénaff, Noah Alexander, Samuel S. Minot, David Danko, Jonathan Foox, Sofia Ahsanuddin, Scott W. Tighe, Nur A. Hasan, Poorani Subramanian, Kelly S. Moffat, Shawn Levy, , Christopher E. Mason

This study benchmarks eleven metagenomic classifiers using 846 species and evaluates strategies to reduce false positives in taxonomic classification.

Genome biology · Sep 21, 2017Peer-reviewedGenomics