Jenny Xiang

This study uses single-cell RNA sequencing to show that SOCE blockers BTP2 and CM4620 reduce cytotoxicity in CD8 T cells and NK cells while preserving anti-inflammatory programs in CD4 Tregs.

The paper develops vascularized macrophage-islet organoids to study immune-mediated β cell pyroptosis during viral infection and identifies TNFSF12-TNFRSF12A as a key mechanism.

The paper identifies four SNPs in the LILRB3 gene associated with graft failure in African American kidney transplant recipients and links them to immune-related diseases.

This study shows that inhibiting NOX2 reduces capillary stalling and inflammation in Alzheimer's mice, improving memory and blood flow.

This study uses rapid diagnostics and metatranscriptomics to analyze SARS-CoV-2 infection, revealing viral evolution, host responses, and drug interactions in NYC samples.

The paper assesses DNA sequencing performance across multiple platforms using human and bacterial reference genomes to evaluate quality and reproducibility.

This study identifies transcriptomic changes in mouse ischemic cerebral microvessels and finds shared alterations with human stroke data, highlighting pathways relevant for preclinical research.

This study reports that 17% of advanced cancer patients have clinically relevant germline variants, with higher rates of cancer-associated variants compared to control cohorts.

The paper predicts long-term kidney graft function using exome sequencing by analyzing amino acid mismatches between recipients and donors.