Jae Kyu Ryu

This study shows that blocking fibrin-induced microglia activation reduces neuronal hyperactivity and restores the neuroimmune interactome in Alzheimer's disease.

This study shows that blocking fibrin-microglia interactions reduces AD-related brain network dysfunction and behavioral issues in mice.

This paper develops a novel mouse model of cerebral adrenoleukodystrophy (cALD) that replicates human disease features and highlights NLRP3 inflammasome activation in lesion pathogenesis.