Kelli Lauderdale

This study shows that blocking fibrin-induced microglia activation reduces neuronal hyperactivity and restores the neuroimmune interactome in Alzheimer's disease.

This study shows that blocking fibrin-microglia interactions reduces AD-related brain network dysfunction and behavioral issues in mice.

This study identifies cGAS-mediated IFN-I signaling as a driver of disease progression in drug-refractory epilepsy, showing that targeting cGAS reduces epileptic phenotypes and inflammation.

This study investigates how APOE4 and Aβ interact in preclinical Alzheimer's disease, finding their synergistic effects on neuronal proteostasis and network dysfunction.

This study shows that exposure to anti-GluN1 mAb during development causes long-term sensory-motor deficits and callosal axon changes in mice.

This study shows that both pyramidal neurons and astrocytes swell in hypoosmolar conditions, challenging the notion of neuronal osmoresistance and revealing an AQP4-independent mechanism for osmotic swelling.