Liwei Deng

This study sequences the M13 virus genome using a new single molecule sequencing platform with 100% coverage and consensus sequence accuracy.

This study uses single molecule sequencing of cell-free DNA from maternal plasma to detect trisomy 13, 18, and 21 with improved sensitivity and reduced GC bias compared to NGS.

The paper resequences the E. coli genome using the GenoCare single molecule sequencing platform and shows comparable performance to the Illumina MiSeq system.

This paper introduces a single molecule targeted sequencing technology for cancer gene mutation detection that reduces sample preparation and avoids PCR biases.