Luyang Zhao

OCellus is a language model that addresses limitations in single-cell, spatial, and perturbation biology by integrating natural-language reasoning across multiple tasks.

This paper introduces AICall, a deep learning model that improves basecalling accuracy in NGS by using a spatiotemporal attention mechanism, achieving an error rate below 0.01%.

This paper introduces a sequencing-based spatial transcriptomics system with sub-cellular resolution and significantly improved capture efficiency compared to existing methods.

This study sequences the M13 virus genome using a new single molecule sequencing platform with 100% coverage and consensus sequence accuracy.

The paper resequences the E. coli genome using the GenoCare single molecule sequencing platform and shows comparable performance to the Illumina MiSeq system.

This paper introduces a single molecule targeted sequencing technology for cancer gene mutation detection that reduces sample preparation and avoids PCR biases.