Sensorineural regulation of skull healing implicates FGF1 signaling in non-healing bone
Allison L Horenberg, Carlos U. Villapudua, Mingxin Xu…·Warren L. Grayson
The paper identifies FGF1 signaling as a sensorineural-skeletal interaction that impairs bone healing in critical-sized defects by promoting osteoprogenitor proliferation and inhibiting differentiation.