Aaron M. Jasnow

An amygdala-cortical circuit for encoding generalized fear memories.

This study identifies an amygdala-cortical circuit involved in encoding generalized fear memories, showing the ACC's role in extracting general threat features rather than specific contextual information.

Restoring DSCAM expression rescues neuronal morphology and axon guidance deficits in Down syndrome

The functional role of locus coeruleus microglia in the female stress response

This study uses chemogenetics to inhibit microglia in the locus coeruleus of female rats, showing reduced inflammation and hypervigilant behavior in response to social stress.

Lessons learned while evaluating how pairing aversive experiences with same or different sex social stimulus mice affects subsequent social engagement

The paper evaluates a modified social stress paradigm in mice to assess sex-inclusive social conditioning, finding males exhibit social avoidance while females do not form social stimulus associations.

Sex divergent behavioral responses in platform-mediated avoidance and glucocorticoid receptor blockade

The paper investigates sex differences in avoidance learning and extinction in mice, finding that glucocorticoid receptor blockade reduces persistent avoidance in females but not males.

Anterior cingulate cortex and ventral hippocampal inputs to the basolateral amygdala selectively control generalized fear

The paper investigates how projections from the anterior cingulate cortex (ACC) and ventral hippocampus (vHPC) to the basolateral amygdala (BLA) regulate generalized fear in mice, showing distinct time-dependent roles for each circuit.