Brian Wysolmerski

This study investigates how GPCRs regulate G protein activity on endosomes using conformational biosensors, finding that endocytosis is required for active Gs production on endosomes.

This study shows that dynein forces on ruptured nuclei counteract lamin-mediated nuclear envelope repair in C. elegans embryos, affecting NE rupture duration and recovery.

The paper shows that C. elegans heterochromatin proteins collaborate with piRNA and nuclear RNAi pathways to silence repetitive elements and prevent germline stress.