Author

Andrew N. Dates

Harvard UniversityORCID 0000-0001-9307-5973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Stephen C. BlacklowiD· 2 shared Abigail GilmeriD· 1 shared Alexandre P. J. MartiniD· 1 shared Andrew C. KruseiD· 1 shared Ari S. HilibrandiD· 1 shared Asuka InoueiD· 1 shared Brian WysolmerskiiD· 1 shared Chanpreet JassaliD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

Stephen C. BlacklowORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

β-arrestin recruitment facilitates a direct association with G proteins

Claudia Y. Lee, Jeffrey S. Smith, Taylor Kohlmann, Emily M. Meara, Uyen Pham, Frank Kwarcinski, Andrew N. Dates, Jessica K. Orofino, Issac Choi, Ari S. Hilibrand, Chanpreet Jassal, Abigail Gilmer, Stephen C. Blacklow, Gregory G. Tall, Andrew C. Kruse, Sudarshan Rajagopal

This study shows that G proteins and β-arrestins can directly interact, with Gi family members differing in their association with β-arrestin, and this selectivity is located in the alpha helical domain of Gi.

Nature Communications · Jul 17, 2026Peer-reviewedBiochemistry

Conformational biosensors delineate endosomal G protein regulation by GPCRs

Brian Wysolmerski, Nicole M. Fisher, Andrew N. Dates, Asuka Inoue, Emily E. Blythe, Mark von Zastrow

This study investigates how GPCRs regulate G protein activity on endosomes using conformational biosensors, finding that endocytosis is required for active Gs production on endosomes.

Nature Communications · Feb 18, 2026Peer-reviewedCell Biology

A Spatiotemporal Notch Interaction Map from Membrane to Nucleus

Alexandre P. J. Martin, Gary Andrew Bradshaw, Robyn J. Eisert, Emily D. Egan, Lena Tveriakhina, Julia M. Rogers, Andrew N. Dates, Gustavo Scanavachi, Jon Christopher Aster, Tomas L. Kirchhausen, Marian Kalocsay, Stephen C. Blacklow

This study maps the spatiotemporal dynamics of Notch2 signaling from membrane to nucleus after ligand activation, identifying key molecular events in signal transmission.

bioRxiv · Dec 21, 2022 · PreprintMolecular Biology