Author

Chengchao Ding

University of Science and Technology of ChinaORCID 0000-0002-4058-2725Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Fushun ZhangiD· 1 shared Saori UematsuiD· 1 shared Shu‐Bing QianiD· 1 shared Xinyi Ashley Liu· 1 shared Yan XiangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMolecular Biology

Fushun ZhangORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 4, 2026

Selective targeting of type II tRNAs underlies SLFN14-mediated translational repression and its dysregulation by thrombocytopenia-linked mutations

Chengchao Ding, Xinyi Ashley Liu, Fushun Zhang…·Yan Xiang

This study identifies SLFN14 as a ribosome-associated endoribonuclease that represses translation by selectively cleaving type II tRNAs, and shows how mutations linked to thrombocytopenia disrupt this mechanism.

DOI 10.64898/2026.02.03.703619

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