Shu‐Bing Qian

The paper profiles terminating ribosomes to show sequence-dependent pausing at stop codons and its impact on translation fidelity and protein diversity.

This study identifies SLFN14 as a ribosome-associated endoribonuclease that represses translation by selectively cleaving type II tRNAs, and shows how mutations linked to thrombocytopenia disrupt this mechanism.

The paper identifies a metabolic connection between PI4P and PA at the plasma membrane, showing how PI4P depletion increases PA levels through PS synthesis and RhoB activation.

The paper shows that DRMY1 sustains translation of cytokinin signaling inhibitors, ensuring robust sepal development in Arabidopsis by maintaining auxin patterning.

The paper shows that cells use an adaptive pausing response to survive severe stress by pausing translation and limiting ATP use, followed by recovery through ISR signaling.

The paper identifies m6A methylation in the 5' vicinity of transcripts as a mechanism for directing mRNAs to stress granules via YTHDF3 recognition during oxidative stress.