Cancer BiologyGenes & DiseasesPeer-reviewed
In Vivo Multiplexed Modeling Reveals Diverse Roles of the TBX2 Subfamily and Egr1 in Ras-Driven Lung Adenocarcinoma
Athar Khalil, Trang Dinh, Meaghan Parks…·Christopher D. McFarland
The paper develops a multiplexed mouse model to study TBX2 subfamily and Egr1 roles in Ras-driven lung cancer, finding Egr1 loss significantly increases tumor size and suggests immune dysregulation.
DOI 10.1016/j.gendis.2025.101840