Author

Trang Dinh

Case Western Reserve UniversityORCID 0000-0003-4833-9161Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Zhenghe WangiD· 3 shared Rebecca C. ObengiD· 2 shared Adam M. KresakiD· 1 shared Alexandra A. WolfarthiD· 1 shared Athar KhaliliD· 1 shared Berkley E. GryderiD· 1 shared Christopher D. McFarlandiD· 1 shared Dathan AndrewsiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCancer Biology

Zhenghe WangORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 15, 2025

Efineptakin alfa (NT-I7) improves overall survival and induces tertiary lymphoid structures in murine lung tumors

Trang Dinh, Judong Lee, Sidra Islam…·Rebecca C. Obeng

This study shows efineptakin alfa (NT-I7) improves survival and induces tertiary lymphoid structures in murine lung tumors, potentially enhancing immunotherapy efficacy.

DOI 10.1101/2025.09.15.676444

mousespatial transcriptomics

𝕏 PostBluesky

Cancer BiologyGenes & DiseasesPeer-reviewedSep 3, 2025

In Vivo Multiplexed Modeling Reveals Diverse Roles of the TBX2 Subfamily and Egr1 in Ras-Driven Lung Adenocarcinoma

Athar Khalil, Trang Dinh, Meaghan Parks…·Christopher D. McFarland

The paper develops a multiplexed mouse model to study TBX2 subfamily and Egr1 roles in Ras-driven lung cancer, finding Egr1 loss significantly increases tumor size and suggests immune dysregulation.

DOI 10.1016/j.gendis.2025.101840

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyInterdisciplinary Information SciencesPeer-reviewedJan 1, 2025

CRISPR/Cas9 screenings reveal the role of STX1A and CDK1 in Cathepsin G entering and killing colorectal cancer cells

Yuxiang Wang, Valery Rozen, Trang Dinh…·Zhenghe Wang

This study identifies STX1A and CDK1 as key factors in CTSG-mediated entry and killing of colorectal cancer cells through CRISPR/Cas9 screens.

2 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky