Andrea KH Stavoe

PP2A and CDK16 antagonistically regulate WIPI2B phosphorylation and neuronal autophagosome biogenesis

This study identifies PP2A and CDK16 as regulators of WIPI2B phosphorylation and neuronal autophagosome biogenesis, showing their antagonistic roles in this process.

Different forms of autophagy restrict neurite outgrowth in disparate compartments in a single neuron

The paper investigates how different forms of autophagy restrict neurite outgrowth in distinct neuronal compartments in C. elegans neurons.

Endogenous autophagosome reporters reveal redundant and non-redundant roles of LGG-1 and LGG-2 in C. elegans neuronal autophagy

Spatial confinement shapes organelle architecture and remodeling in axons

The paper uses cryo-electron tomography to study axonal organelle organization, revealing how spatial confinement influences membrane remodeling and organelle morphology.

Sex does not Influence Neuronal Autophagy throughout Aging in Mice

The paper examines sex differences in neuronal autophagy across aging in mice and finds no significant sex-related differences in autophagy protein expression or autophagosome formation.

Aging Differentially Affects Axonal Autophagosome Formation and Maturation

This study examines how aging affects autophagosome formation and maturation in murine neurons, finding reduced formation but increased maturation in aged neurons.

Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons

This study shows that WIPI2B expression counteracts age-related decline in autophagosome biogenesis in neurons, suggesting it as a therapeutic target for age-associated neurodegeneration.