Author

Avani Bharat Parikh

University of PittsburghORCID 0000-0002-4083-0987Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander DeitersiD· 2 shared Elisa RuffoiD· 2 shared Jason J. LohmuelleriD· 2 shared Michael KvorjakiD· 2 shared Victor SoiD· 2 shared Yaniv TivoniD· 2 shared Adam ButchyiD· 1 shared Eric L. Adams· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Alexander DeitersORCID

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2 papers

Recent·Most cited

Synthetic BiologyACS Synthetic BiologyPeer-reviewedOct 4, 2023

Conditional control of universal CAR T cells by cleavable OFF-switch adaptors.

Michael Kvorjak, Elisa Ruffo, Yaniv Tivon…·Jason J. Lohmueller

This paper introduces OFF-switch adaptors to conditionally control universal CAR T cells using small molecules or light, enabling precise targeting and enhanced safety.

23 citations

experimental assaydrug response / drug discovery

Synthetic BiologyNature CommunicationsPeer-reviewedMay 9, 2023

Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting

Elisa Ruffo, Adam Butchy, Yaniv Tivon…·Jason J. Lohmueller

This paper introduces SNAP-CAR and SNAP-synNotch receptors that can be post-translationally targeted by BG-conjugated antibodies to activate T cell signaling or gene programs in an antigen-specific manner.

72 citationstop 2%

statistical model