Author

Nilesh W. Gaikwad

ORCID 0000-0002-4087-3266Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

Marco BortolatoiD· 2 shared Roberto CadedduiD· 2 shared Eva VigatoiD· 1 shared Gabriel D. BosséiD· 1 shared Gabriele FlorisiD· 1 shared Gian Michele RattoiD· 1 shared Kristen A. KeefeiD· 1 shared Laura J. Mosher· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Marco BortolatoORCID

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2 papers

Recent·Most cited

Acute stress impairs sensorimotor gating via the neurosteroid allopregnanolone in the prefrontal cortex

Roberto Cadeddu, Laura J. Mosher, Peter Nordkild, Nilesh W. Gaikwad, Gian Michele Ratto, Simona Scheggi, Marco Bortolato

This study shows acute stress impairs sensorimotor gating by increasing allopregnanolone in the prefrontal cortex, which can be reversed by blocking allopregnanolone.

Neurobiology of Stress · Sep 24, 2022Peer-reviewedNeuroscience

The 5α-reductase inhibitor finasteride reduces opioid self-administration

Gabriel D. Bossé, Roberto Cadeddu, Gabriele Floris, Ryan D. Farero, Eva Vigato, Suhjung Janet Lee, Tejia Zhang, Nilesh W. Gaikwad, Kristen A. Keefe, Paul E.M. Philips, Marco Bortolato, Randall Theodore Peterson

This study shows finasteride reduces opioid self-administration in zebrafish and rats without affecting locomotion or feeding, and suggests steroidogenic pathways as potential targets for OUD treatment.

bioRxiv · Sep 15, 2020 · PreprintNeuroscience