Author

Jolien Suurmond

Leiden University Medical CenterORCID 0000-0002-4092-8925Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Annemarie L Dorjée· 2 shared René E. M. ToesiD· 2 shared Tom W. J. HuizingaiD· 2 shared Annette Grummels· 1 shared Betty DiamondiD· 1 shared Cynthia B. AranowiD· 1 shared Esther van Andel· 1 shared Gerda M. Steup-Beekman· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Annemarie L Dorjée

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2 papers

Recent·Most cited

Symmetrical Dimethylarginine as the Central Antigenic Determinant of Anti-Smith Autoantibodies in Systemic Lupus Erythematosus

Lars C. van Vliet, Annemarie L Dorjée, Martijn van der Heide, Annette Grummels, Esther van Andel, Gerda M. Steup-Beekman, Tom W. J. Huizinga, René E. M. Toes, Jolien Suurmond

This study identifies symmetrical dimethylarginine (sDMA) as the central antigenic determinant recognized by anti-Smith autoantibodies in SLE, showing their high cross-reactivity to sDMA-containing viral epitopes.

Annals of the Rheumatic Diseases · Jul 10, 2026Peer-reviewedImmunology

IFN-associated B cell hyperactivity is highly enriched in SLE patients harboring Sm/RNP antibodies

Hugo J. van Dooren, Yemil Atisha‐Fregoso, Annemarie L Dorjée, Tom W. J. Huizinga, Meggan C. Mackay, Cynthia B. Aranow, René E. M. Toes, Betty Diamond, Jolien Suurmond

The paper identifies a subgroup of SLE patients with high plasmablast frequency and IFN signature, enriched in those with Sm/RNP antibodies, linking IFN to B cell hyperactivity and autoantibody production.

Journal of Autoimmunity · May 25, 2025Peer-reviewedImmunology