Characterization of Histone Lysine β-hydroxybutyrylation in bovine tissues, cells, and cumulus-oocyte complexes
Juliano Rodrigues Sangalli, Ricardo Perecin Nociti, Maite del Collado, Rafael Vilar Sampaio, Juliano Coelho da Silveira, Felipe Perecin, Lawrence Charles Smith, Pablo J. Ross, Flávio Vieira Meirelles
The paper investigates the effects of beta-hydroxybutyrate on histone lysine beta-hydroxybutyrylation and transcriptome changes in bovine fibroblasts and cumulus-oocyte complexes, showing altered gene expression but no impact on oocyte meiotic competence.
Molecular Reproduction and Development · Jul 8, 2022Peer-reviewedDevelopmental Biology