Shahar Kasirer

This study shows that mechanical stress influences age-related changes in vestibular hair cell differentiation and regeneration through Notch signaling.

The paper shows that morphological differences influence Notch-mediated lateral inhibition, biasing cells toward signal-sending or receiving roles during neuroblast selection.

The paper identifies a rare subpopulation of cochlear supporting cells that transdifferentiate into hair cells upon Notch inhibition, revealing epigenetic and transcriptional changes associated with this process.

This study identifies a mechano-signaling feedback mechanism that drives precise inner hair cell patterning in the organ of Corti through coordinated cellular movements and adhesion.