Author

Roie Cohen

Tel Aviv UniversityORCID 0000-0002-9018-0580Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

David SprinzakiD· 3 shared Olga LozaiD· 3 shared Shahar TaiberiD· 2 shared Shiran WolandiD· 2 shared Fumio MatsuzakiiD· 1 shared Karen B. AvrahamiD· 1 shared Liat Amir-Zilberstein· 1 shared Micha HerschiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersDevelopmental Biology

David SprinzakORCID

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3 papers

Recent·Most cited

The Fat4 intracellular domain controls turnover of Fat4/Dchs1 planar polarity membrane complexes

Yathreb Easa, Olga Loza, Roie Cohen, David Sprinzak

This study investigates how the intracellular domain of Fat4 regulates the turnover and dynamics of Fat4/Dchs1 planar polarity complexes using live imaging.

Biophysical Journal · Feb 14, 2025Peer-reviewedCell Biology

Mechano-signaling feedback underlies precise inner hair cell patterning in the organ of Corti

Roie Cohen, Shahar Taiber, Olga Loza, Shahar Kasirer, Shiran Woland, David Sprinzak

This study identifies a mechano-signaling feedback mechanism that drives precise inner hair cell patterning in the organ of Corti through coordinated cellular movements and adhesion.

bioRxiv · Jan 24, 2022 · PreprintDevelopmental Biology

Shear forces drive precise patterning of hair cells in the mammalian inner ear

Roie Cohen, Liat Amir-Zilberstein, Micha Hersch, Shiran Woland, Olga Loza, Shahar Taiber, Fumio Matsuzaki, Sven Bergmann, Karen B. Avraham, David Sprinzak

This study shows that shear forces and local repulsion drive the formation of the checkerboard pattern of hair cells in the mammalian inner ear.

Nature Communications · Oct 12, 2020Peer-reviewedDevelopmental Biology