Bingjie Zhang

This study shows that inhibiting DHODH promotes NK cell infiltration and activates cGAS-STING and pyroptosis pathways, enhancing anti-tumor immunity in melanoma.

This study identifies NEK1's role in motor neuron neurite outgrowth by coordinating retromer formation through interactions with SMC3.

The paper characterizes antigen-specific CD8+ T cells post-SARS-CoV-2 vaccination and infection using multimodal sequencing, identifying unique biomarkers and clinical predictors.

The paper introduces scCUT&Tag-pro and scChromHMM to analyze chromatin states in single cells, showing their ability to characterize dynamic changes and regulatory priming across immune cell types.

This paper introduces NTT-seq, a method to measure multiple chromatin features at single-cell resolution, and demonstrates its application in immune cells.

The paper shows that global DNA methylation inheritance and enhancer dememorization in zebrafish embryos protect embryonic gene programs by preventing ectopic gene activation.