Author

Pin Wang

University of Southern CaliforniaORCID 0000-0002-4132-105XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Jennifer A. RohrsiD· 2 shared Nicholas Alexander GrahamiD· 2 shared Stacey D. FinleyiD· 2 shared Alireza DelfarahiD· 1 shared Dongqing Zheng· 1 shared Elizabeth L. SiegleriD· 1 shared Frances Seo· 1 shared Jason A. JungeiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersSystems Biology

Jennifer A. RohrsORCID

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3 papers

Recent·Most cited

Systems BiologyiSciencePeer-reviewedMar 30, 2020

ERK activation in CAR T cells is amplified by CD28-mediated increase in CD3ζ phosphorylation

Jennifer A. Rohrs, Elizabeth L. Siegler, Pin Wang, Stacey D. Finley

The paper constructs a computational model of CAR T cell activation, showing CD28 enhances ERK activation by increasing CD3ζ phosphorylation kinetics.

38 citations

statistical model

𝕏 PostBluesky

Systems BiologyJournal of Biological ChemistryPeer-reviewedMay 28, 2019

Inhibition of nucleotide synthesis promotes replicative senescence of human mammary epithelial cells

Alireza Delfarah, Sydney Parrish, Jason A. Junge…·Nicholas Alexander Graham

This study shows that inhibiting nucleotide synthesis induces replicative senescence in human mammary epithelial cells by blocking metabolic flux into nucleotide pathways.

51 citations

humanmetabolomics

𝕏 PostBluesky

Systems BiologyBiophysical JournalPeer-reviewedAug 22, 2018

Computational model of chimeric antigen receptors explains site-specific phosphorylation kinetics

Jennifer A. Rohrs, Dongqing Zheng, Nicholas Alexander Graham…·Stacey D. Finley

The paper develops a computational model to explain site-specific phosphorylation kinetics of CARs using phospho-proteomic data and mechanistic modeling.

45 citations

proteomicsstatistical model

𝕏 PostBluesky