The PUF RNA-binding protein, FBF-2, maintains stem cells without binding to RNA
Brian H. Carrick, Sarah L. Crittenden, MaryGrace Linsley, Stephany J. Costa Dos Santos, Marvin Wickens, Judith E. Kimble
The paper shows that FBF-2, a PUF RNA-binding protein, maintains stem cells even when it cannot bind RNA, indicating that RNA-binding is not essential for its biological activity.
RNA · Feb 21, 2025Peer-reviewedDevelopmental Biology