Author

Robert C. Dutcher

National Institutes of HealthORCID 0000-0002-5144-2111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Traci M. Tanaka HalliD· 3 shared Aaron C. GoldstrohmiD· 1 shared Amanda J KorteiD· 1 shared Andrei A. KorosteleviD· 1 shared Brenna A SaladiniD· 1 shared Brian H. CarrickiD· 1 shared Chen Qiu· 1 shared Chen QiuiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMolecular Biology

Traci M. Tanaka HallORCID

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3 papers

Recent·Most cited

Molecular BiologyJournal of Biological ChemistryPeer-reviewedFeb 13, 2026

Human Pumilio proteins use fuzzy multivalent hydrophobic interactions to recruit the CCR4-NOT deadenylase complex to repress mRNAs

Elise B. Dunshee, Brenna A Saladin, David J. Turner…·Aaron C. Goldstrohm

The paper identifies how human PUM proteins repress mRNAs by using fuzzy multivalent hydrophobic interactions to recruit the CCR4-NOT deadenylase complex through their intrinsically disordered RD3 domain.

1 citation

humanexperimental assay

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BiochemistryNature CommunicationsPeer-reviewedJan 2, 2025

A higher order PUF complex is central to regulation of C. elegans germline stem cells

Chen Qiu, Sarah L. Crittenden, Brian H. Carrick…·Traci M. Tanaka Hall

The paper identifies a ternary PUF complex in C. elegans that regulates germline stem cells by repressing and activating gld-1 mRNA through adjacent FBEs.

5 citations

C. elegansmetagenomics

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Molecular BiologyMolecular CellPeer-reviewedSep 30, 2022

Structural Basis of MicroRNA Biogenesis by Dicer-1 and Its Partner Protein Loqs-PB

Karina Jouravleva, Dmitrij Golovenko, Gabriel Demo…·Andrei A. Korostelev

The paper reports cryo-EM structures of Drosophila Dicer-1 and Loqs-PB complex during pre-miRNA processing, revealing the mechanism of miRNA biogenesis.

57 citationstop 2%

Drosophilaexperimental assay

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