Ex vivo and in vivo HIV-1 latency reversal by Mukungulu, a protein kinase C-activating African medicinal plant extract
Khumoekae Richard, Zhe Yuan, Hsin‐Yao Tang, Aaron R. Goldman, Riza Kuthu, Boingotlo Raphane, Emery T. Register, Paridhima Sharma, Brian N. Ross, Jessicamarie Morris, David E. Williams, Carol A. Cheney, Guoxin Wu, Karam Mounzer, Gregory M. Laird, , Luis J. Montaner
This study shows that Mukungulu, an African medicinal plant extract, effectively reverses HIV-1 latency in humanized mice and human cells, outperforming standard controls.
mBio · Apr 23, 2025Peer-reviewedMicrobiology