Gregory M. Laird

The paper uses scRNA-seq to show that monocyte IL1B expression inversely correlates with HIV-1 reservoir size in ART-treated individuals.

This study shows that Mukungulu, an African medicinal plant extract, effectively reverses HIV-1 latency in humanized mice and human cells, outperforming standard controls.

This study identifies Retinol Binding Protein 4 (RBP4) as a natural activator of latent HIV-1 through JAK/STAT5 and JNK pathways, offering a new strategy for reactivating viral reservoirs.

This paper demonstrates that PZ703b, a dual Bcl-2/Bcl-xL degrader, reverses HIV latency and reduces the replication-competent reservoir in ex vivo CD4+ T cells from ART-suppressed patients.